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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
34.55
Human Site:
Y127
Identified Species:
58.46
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
Y127
M
L
N
K
E
K
T
Y
L
R
D
Q
H
F
L
Chimpanzee
Pan troglodytes
XP_512559
393
44800
H119
D
Q
H
F
L
E
Q
H
P
L
L
Q
P
K
M
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
Y127
M
L
N
K
E
K
T
Y
L
R
D
Q
H
F
L
Dog
Lupus familis
XP_541724
456
51105
Y173
M
L
N
K
E
K
T
Y
L
R
D
K
H
F
M
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
Y125
M
L
N
K
E
K
T
Y
L
R
D
E
H
F
L
Rat
Rattus norvegicus
P39949
411
47463
Y128
M
L
N
K
E
K
T
Y
L
R
D
E
H
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
Y125
L
L
N
K
E
T
K
Y
V
H
D
K
H
F
E
Chicken
Gallus gallus
P49707
407
46720
Y124
M
I
N
K
E
E
T
Y
V
R
D
K
L
Y
M
Frog
Xenopus laevis
Q91780
408
47153
Y126
M
L
N
K
D
R
I
Y
L
R
D
K
N
F
F
Zebra Danio
Brachydanio rerio
P47794
410
46612
Y129
L
L
G
K
D
K
L
Y
L
R
D
T
R
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
D342
M
C
H
R
D
E
Q
D
S
R
L
R
S
I
S
Honey Bee
Apis mellifera
XP_394802
457
51232
T133
M
C
L
G
D
Q
K
T
I
T
Q
R
N
P
Q
Nematode Worm
Caenorhab. elegans
O01501
524
60567
P244
M
V
K
R
D
E
I
P
R
A
T
R
F
L
L
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
L137
I
M
T
R
K
E
A
L
C
P
R
K
H
D
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
93.3
N.A.
53.3
53.3
60
46.6
N.A.
13.3
6.6
13.3
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
73.3
93.3
86.6
66.6
N.A.
46.6
40
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
15
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
36
0
0
8
0
0
65
0
0
8
0
% D
% Glu:
0
0
0
0
50
36
0
0
0
0
0
15
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
50
8
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
8
0
8
0
0
50
0
0
% H
% Ile:
8
8
0
0
0
0
15
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
8
65
8
43
15
0
0
0
0
36
0
8
0
% K
% Leu:
15
58
8
0
8
0
8
8
50
8
15
0
8
8
36
% L
% Met:
72
8
0
0
0
0
0
0
0
0
0
0
0
0
29
% M
% Asn:
0
0
58
0
0
0
0
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
8
0
0
8
8
0
% P
% Gln:
0
8
0
0
0
8
15
0
0
0
8
22
0
0
8
% Q
% Arg:
0
0
0
22
0
8
0
0
8
65
8
22
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% S
% Thr:
0
0
8
0
0
8
43
8
0
8
8
8
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
15
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _